Developing high-producing and robust processes
GenScript ProBio has established one-stop biologics development and manufacturing capabilities, it takes as fast as 6 months from gene synthesis to tox batch completion.
GenScript ProBio has established ProBoxTM, an optimized process development tool box to analyze different types of bispecific antibodies and proteins, provides solutions and solves the challenging problems with our expertise on the knowledge of protein structures and quality attributes.
90+ CMC & CMO Projects
24 Global IND Approvals
mAb Fast CMCFor mAb, Naked Ab of ADC
6 months from Sequence to Tox batch completion
bsAb Fast CMCFor bsAb
As fast as 7 months from Sequence to Tox batch completion
Intensified CMCFor bsAb, Protein
9 months from Sequence to Tox batch completion
√ 6 months from sequence to Tox√ 12 months from sequence to IND√ 0.5kg/200L, 1.2kg/500L GMP DS is guaranteed to deliver
Applicable to symmetrical bispecific antibody：√ 7 months from sequence to Tox √ 13 months from sequence to IND
Applicable to asymmetrical bispecific antibody：√ 8.5 months from sequence to Tox √ 14.5 months from sequence to IND
Intensified CMC Highlights
Intensified CMC Significantly Brings Titer Improvement
80% projects titer increase between 80%-150%
√ ProBoxTM -process development tool box is build based on ProBio’s ~100 CMC project experience and it classifies, summarizes and integrates ~200 technical challenges and solutions in process development and analytical development.
√ The ProBoxTM is updated in real time to help process researchers better cope with new process development challenges.
√ In addition, ProBoxTM analyzes multiple types of bispecific antibodies and proteins and summarizes the challenges and solutions based on the understanding of their structure and quality attributes.
Determine the Biological Potency of Broad Types of Targets
Cell-based assay Dev. Capability
Different kinds of targets
Platforms for characterization
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